Literature DB >> 17296594

The V617F mutation of JAK2 is very uncommon in patients with thrombosis.

Angel F Remacha, Camino Estivill, M Pilar Sarda, José Mateo, Joan Carles Souto, Carme Canals, Josep Nomdedéu, Jordi Fontcuberta.   

Abstract

Given that many cases of thrombosis do not have a clear cause, a myeloproliferative disease could be involved. We investigated the V617F mutation of the JAK2 gene in 295 patients with thrombosis. Only one case was positive. Therefore, the study of this mutation is not necessary in all patients with idiopathic thrombosis.

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Year:  2007        PMID: 17296594     DOI: 10.3324/haematol.10358

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  2 in total

1.  JAK2V617F mutation in patients with splanchnic vein thrombosis.

Authors:  Sandra Guerra Xavier; Telma Gadelha; Glicínia Pimenta; Angela Maria Eugenio; Daniel Dias Ribeiro; Fernanda Mendes Gomes; Martin Bonamino; Ilana Renault Zalcberg; Nelson Spector
Journal:  Dig Dis Sci       Date:  2009-08-19       Impact factor: 3.199

2.  Relevance of the JAK2V617F mutation in patients with deep vein thrombosis of the leg.

Authors:  Mandy N Lauw; Erik W N Bus; Alexander F Y van Wulfften Palthe; Michiel Coppens; Christa H Homburg; Saskia Middeldorp; C Ellen van der Schoot; Harry R Koene; Bart J Biemond
Journal:  Ann Hematol       Date:  2011-04-12       Impact factor: 3.673

  2 in total

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