PURPOSE: To evaluate the usefulness of EEG-combined functional magnetic resonance imaging (EEG-fMRI) to localize epileptogenic sources. METHODS: Six children (age 8-15 years) with lesional or nonlesional pharmacoresistant focal epilepsy were studied. RESULTS: We found significant activations in four children, activation and deactivation in one child, and widespread deactivation in another. In four children, activations colocalized with the presumed location of the epileptic focus, one of which was confirmed by intracranial EEG. CONCLUSIONS: EEG-fMRI is a promising tool to noninvasively localize epileptogenic regions in children with pharmacoresistant focal epilepsy.
PURPOSE: To evaluate the usefulness of EEG-combined functional magnetic resonance imaging (EEG-fMRI) to localize epileptogenic sources. METHODS: Six children (age 8-15 years) with lesional or nonlesional pharmacoresistant focal epilepsy were studied. RESULTS: We found significant activations in four children, activation and deactivation in one child, and widespread deactivation in another. In four children, activations colocalized with the presumed location of the epileptic focus, one of which was confirmed by intracranial EEG. CONCLUSIONS: EEG-fMRI is a promising tool to noninvasively localize epileptogenic regions in children with pharmacoresistant focal epilepsy.
Authors: Julia Jacobs; Colin Hawco; Eliane Kobayashi; Rainer Boor; Pierre LeVan; Ulrich Stephani; Michael Siniatchkin; Jean Gotman Journal: Neuroimage Date: 2007-12-15 Impact factor: 6.556
Authors: Simon Tousseyn; Patrick Dupont; Karolien Goffin; Stefan Sunaert; Wim Van Paesschen Journal: Front Neurol Date: 2014-07-17 Impact factor: 4.003
Authors: Sahana Ramanathan; Govindaraju Archunan; Muthusamy Sivakumar; Subramanian Tamil Selvan; A Lenin Fred; Sundramurthy Kumar; Balázs Gulyás; Parasuraman Padmanabhan Journal: Int J Nanomedicine Date: 2018-09-20