Literature DB >> 17295383

Ursolic acid: a potent inhibitor of superoxides produced in the cellular system.

Muhammad S Ali1, Syed A Ibrahim, Saima Jalil, Muhammad I Choudhary.   

Abstract

Triterpenoids of ursane class: ursolic acid, ilelatifol D, corosolic acid and euscaphic acid were isolated for the first time from Leonurus cardiaca, a member of the family Lamiaceae. The isolated compounds were tested for their cell-based antiinflammatory potential by suppressing respiratory burst activity and superoxide scavenging property by using xanthine/xanthine oxidase system to produce superoxides in the cell-free system. Ursolic acid was found to be an excellent inhibitor for the superoxides produced in the cellular system, while the same was inactive in the superoxide scavenging activity in cell-free system. (c) 2007 John Wiley & Sons, Ltd.

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Year:  2007        PMID: 17295383     DOI: 10.1002/ptr.2108

Source DB:  PubMed          Journal:  Phytother Res        ISSN: 0951-418X            Impact factor:   5.878


  12 in total

1.  Ursolic acid isolated from Isodon excisoides induces apoptosis and inhibits invasion of GBC-SD gallbladder carcinoma cells.

Authors:  Huiping Chen; Xiujuan Wu; Yitao Duan; Dexian Zhi; Min Zou; Zhihong Zhao; Xiaojun Zhang; Xiaoang Yang; Jianying Zhang
Journal:  Oncol Lett       Date:  2019-05-27       Impact factor: 2.967

Review 2.  Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents.

Authors:  Haijun Chen; Yu Gao; Ailan Wang; Xiaobin Zhou; Yunquan Zheng; Jia Zhou
Journal:  Eur J Med Chem       Date:  2015-01-16       Impact factor: 6.514

3.  Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation.

Authors:  Min Kyung Hyun; Dae Hyun Kim; Chan Hum Park; Sang Gyun Noh; Sihyun Choi; Jae Yong Lee; Ji Hye Choi; Duhyeon Park; Yeon Ja Choi; Hae Young Chung
Journal:  J Mol Med (Berl)       Date:  2022-08-13       Impact factor: 5.606

4.  Ursolic acid enhances macrophage autophagy and attenuates atherogenesis.

Authors:  Shuilong Leng; Stephen Iwanowycz; Fatma Saaoud; Junfeng Wang; Yuzhen Wang; Ismail Sergin; Babak Razani; Daping Fan
Journal:  J Lipid Res       Date:  2016-04-10       Impact factor: 5.922

Review 5.  Antimicrobial activity of oleanolic and ursolic acids: an update.

Authors:  Jéssica A Jesus; João Henrique G Lago; Márcia D Laurenti; Eduardo S Yamamoto; Luiz Felipe D Passero
Journal:  Evid Based Complement Alternat Med       Date:  2015-02-22       Impact factor: 2.629

6.  The Study of Analgesic Effects of Leonurus cardiaca L. in Mice by Formalin, Tail Flick and Hot Plate Tests.

Authors:  Masoume Rezaee-Asl; Mandana Sabour; Vahid Nikoui; Sattar Ostadhadi; Azam Bakhtiarian
Journal:  Int Sch Res Notices       Date:  2014-09-01

Review 7.  Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review.

Authors:  Cristina M Uritu; Cosmin T Mihai; Gabriela-Dumitrita Stanciu; Gianina Dodi; Teodora Alexa-Stratulat; Andrei Luca; Maria-Magdalena Leon-Constantin; Raluca Stefanescu; Veronica Bild; Silvia Melnic; Bogdan I Tamba
Journal:  Pain Res Manag       Date:  2018-05-08       Impact factor: 3.037

8.  Potential Protective Effects of Ursolic Acid against Gamma Irradiation-Induced Damage Are Mediated through the Modulation of Diverse Inflammatory Mediators.

Authors:  Hong Wang; Meng-Kwoon Sim; Weng Keong Loke; Arunachalam Chinnathambi; Sulaiman Ali Alharbi; Feng Ru Tang; Gautam Sethi
Journal:  Front Pharmacol       Date:  2017-06-16       Impact factor: 5.810

9.  Cytotoxicity of Triterpenes from Green Walnut Husks of Juglans mandshurica Maxim in HepG-2 Cancer Cells.

Authors:  Yuanyuan Zhou; Bingyou Yang; Zhaoxi Liu; Yanqiu Jiang; Yuxin Liu; Lei Fu; Xiaoli Wang; Haixue Kuang
Journal:  Molecules       Date:  2015-10-22       Impact factor: 4.411

10.  Variation of ursolic acid content in flowers of ten Iranian pomegranate (Punica granatum L.) cultivars.

Authors:  Fatemeh Sharifiyan; Seyed Abbas Mirjalili; Mohammad Fazilati; Elahe Poorazizi; Saeed Habibollahi
Journal:  BMC Chem       Date:  2019-07-03
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