| Literature DB >> 17292372 |
Henry M Staines1, Abdulnaser Alkhalil, Richard J Allen, Hugo R De Jonge, Elvira Derbyshire, Stéphane Egée, Hagai Ginsburg, David A Hill, Stephan M Huber, Kiaran Kirk, Florian Lang, Godfrey Lisk, Eugene Oteng, Ajay D Pillai, Kempaiah Rayavara, Sherin Rouhani, Kevin J Saliba, Crystal Shen, Tsione Solomon, Serge L Y Thomas, Patrick Verloo, Sanjay A Desai.
Abstract
The altered permeability characteristics of erythrocytes infected with malaria parasites have been a source of interest for over 30 years. Recent electrophysiological studies have provided strong evidence that these changes reflect transmembrane transport through ion channels in the host erythrocyte plasma membrane. However, conflicting results and differing interpretations of the data have led to confusion in this field. In an effort to unravel these issues, the groups involved recently came together for a week of discussion and experimentation. In this article, the various models for altered transport are reviewed, together with the areas of consensus in the field and those that require a better understanding.Entities:
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Year: 2007 PMID： 17292372 PMCID： PMC2746352 DOI： 10.1016/j.ijpara.2006.12.013
Source DB: PubMed Journal: Int J Parasitol ISSN： 0020-7519 Impact factor: 3.981