Biocompatible nanofiber scaffolds on metal for controlled release and cell colonization.

This paper reports for the first time a preparation of biocompatible titanate nanofiber scaffolds on the surface of titanium foil/mesh via a one-step hydrothermal reaction. The length and diameter of the nanofibers can be controlled by varying the fabrication parameters, such as reaction temperature, precursor concentration, and reaction time. The nanofibers can self-organize into macroporous (mostly 0.5-10 microm in diameter) scaffolds potentially useful for developing new bioscaffolds, photocatalysts, sensors, and drug delivery vehicles.