Literature DB >> 17292107

Self-assembling nanoclusters in living systems: application for integrated photothermal nanodiagnostics and nanotherapy.

Vladimir P Zharov1, Jin-Woo Kim, David T Curiel, Maaike Everts.   

Abstract

Nanotechnologies represent an unprecedented recent advance that may revolutionize many areas of medicine and biology, including cancer diagnostics and treatment. Nanoparticle-based technologies have demonstrated especially high potential for medical purposes, ranging from diagnosing diseases to providing novel therapies. However, to be clinically relevant, the existing nanoparticle-based technologies must overcome several challenges, including selective nanoparticle delivery, potential cytotoxicity, imaging of nanoparticles, and real-time assessment of their therapeutic efficacy. This review addresses these issues by summarizing the recent advances in medical diagnostics and therapy with a focus on the self-assembly of gold nanoparticles into nanoclusters in live cells, in combination with their detection using photothermal (PT) techniques.

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Year:  2005        PMID： 17292107     DOI： 10.1016/j.nano.2005.10.006

Source DB:  PubMed          Journal:  Nanomedicine        ISSN： 1549-9634            Impact factor:   5.307


  43 in total

1.  Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles.

Authors:  Vladimir P Zharov; Kelly E Mercer; Elena N Galitovskaya; Mark S Smeltzer
Journal:  Biophys J       Date:  2005-10-20       Impact factor: 4.033

Review 2.  Advances in small animal mesentery models for in vivo flow cytometry, dynamic microscopy, and drug screening.

Authors:  Ekaterina I Galanzha; Valery V Tuchin; Vladimir P Zharov
Journal:  World J Gastroenterol       Date:  2007-01-14       Impact factor: 5.742

3.  Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential.

Authors:  Swanand Patil; Amanda Sandberg; Eric Heckert; William Self; Sudipta Seal
Journal:  Biomaterials       Date:  2007-08-01       Impact factor: 12.479

4.  In vivo multispectral, multiparameter, photoacoustic lymph flow cytometry with natural cell focusing, label-free detection and multicolor nanoparticle probes.

Authors:  Ekaterina I Galanzha; Evgeny V Shashkov; Valery V Tuchin; Vladimir P Zharov
Journal:  Cytometry A       Date:  2008-10       Impact factor: 4.355

Review 5.  Gold nanoparticles: From nanomedicine to nanosensing.

Authors:  Po C Chen; Sandra C Mwakwari; Adegboyega K Oyelere
Journal:  Nanotechnol Sci Appl       Date:  2008-11-02

6.  Enhanced detection of early-stage oral cancer in vivo by optical coherence tomography using multimodal delivery of gold nanoparticles.

Authors:  Chang Soo Kim; Petra Wilder-Smith; Yeh-Chan Ahn; Lih-Huei L Liaw; Zhongping Chen; Young Jik Kwon
Journal:  J Biomed Opt       Date:  2009 May-Jun       Impact factor: 3.170

7.  Thermo-optical analysis and selection of the properties of absorbing nanoparticles for laser applications in cancer nanotechnology.

Authors:  Victor K Pustovalov; L G Astafyeva; E Galanzha; V P Zharov
Journal:  Cancer Nanotechnol       Date:  2010-09-07

8.  A facile synthesis of novel self-assembled gold nanorods designed for near-infrared imaging.

Authors:  Dipanjan Pan; Manojit Pramanik; Angana Senpan; Samuel A Wickline; Lihong V Wang; Gregory M Lanza
Journal:  J Nanosci Nanotechnol       Date:  2010-12

Review 9.  Photoacoustic flow cytometry.

Authors:  Ekaterina I Galanzha; Vladimir P Zharov
Journal:  Methods       Date:  2012-06-26       Impact factor: 3.608

Review 10.  Nanotheranostics of circulating tumor cells, infections and other pathological features in vivo.

Authors:  Jin-Woo Kim; Ekaterina I Galanzha; David A Zaharoff; Robert J Griffin; Vladimir P Zharov
Journal:  Mol Pharm       Date:  2013-02-25       Impact factor: 4.939
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