INTRODUCTION: Fulminant hepatic encephalopathy has a high mortality. METHODS: This case report describes the role of cerebral microdialysis as an adjunct to the management of a 49 - year-old woman with hepatic encephalopathy secondary to a paracetamol overdose. RESULTS: The application of the microdialysis technique, by detecting a very low cerebral glucose concentration in the presence of a normal plasma glucose, assisted in clinical decision making. CONCLUSIONS: Cerebral microdialysis, by enabling continuous on-line monitoring of substrate delivery and metabolism, may have a role in the management of patients with fulminant hepatic failure.
INTRODUCTION: Fulminant hepatic encephalopathy has a high mortality. METHODS: This case report describes the role of cerebral microdialysis as an adjunct to the management of a 49 - year-old woman with hepatic encephalopathy secondary to a paracetamol overdose. RESULTS: The application of the microdialysis technique, by detecting a very low cerebral glucose concentration in the presence of a normal plasma glucose, assisted in clinical decision making. CONCLUSIONS: Cerebral microdialysis, by enabling continuous on-line monitoring of substrate delivery and metabolism, may have a role in the management of patients with fulminant hepatic failure.
Authors: R Bullock; A Zauner; J J Woodward; J Myseros; S C Choi; J D Ward; A Marmarou; H F Young Journal: J Neurosurg Date: 1998-10 Impact factor: 5.115
Authors: Bo-Michael Bellander; Emmanuel Cantais; Per Enblad; Peter Hutchinson; Carl-Henrik Nordström; Claudia Robertson; Juan Sahuquillo; Martin Smith; Nino Stocchetti; Urban Ungerstedt; Andreas Unterberg; Niels Vidiendal Olsen Journal: Intensive Care Med Date: 2004-11-10 Impact factor: 17.440
Authors: Josef Prazak; Eva Laszikova; Tomas Pantoflicek; Ondrej Ryska; Eva Koblihova; Miroslav Ryska Journal: BMC Gastroenterol Date: 2013-06-08 Impact factor: 3.067