Literature DB >> 17290030

US multicenter experience with the wingspan stent system for the treatment of intracranial atheromatous disease: periprocedural results.

David Fiorella1, Elad I Levy, Aquilla S Turk, Felipe C Albuquerque, David B Niemann, Beverly Aagaard-Kienitz, Ricardo A Hanel, Henry Woo, Peter A Rasmussen, L Nelson Hopkins, Thomas J Masaryk, Cameron G McDougall.   

Abstract

BACKGROUND AND
PURPOSE: The current report details our initial periprocedural experience with Wingspan (Boston Scientific/Target), the first self-expanding stent system designed for the treatment of intracranial atheromatous disease.
METHODS: All patients undergoing angioplasty and stenting with the Gateway balloon-Wingspan stent system were prospectively tracked.
RESULTS: During a 9-month period, treatment with the stent system was attempted in 78 patients (average age, 63.6 years; 33 women) with 82 intracranial atheromatous lesions, of which 54 were > or =70% stenotic. Eighty-one of 82 lesions were successfully stented (98.8%) during the first treatment session. In 1 case, the stent could not be delivered across the lesion; the patient was treated solely with angioplasty and stented at a later date. Lesions treated involved the internal carotid (n=32; 8 petrous, 10 cavernous, 11 supraclinoid segment, 3 terminus), vertebral (n=14; V4 segment), basilar (n=14), and middle cerebral (n=22) arteries. Mean+/-SD pretreatment stenosis was 74.6+/-13.9%, improving to 43.5+/-18.1% after balloon angioplasty and to 27.2+/-16.7% after stent placement. Of the 82 lesions treated, there were 5 (6.1%) major periprocedural neurological complications, 4 of which ultimately led to patient death within 30 days of the procedure.
CONCLUSIONS: Angioplasty and stenting for symptomatic intracranial atheromatous disease can be performed with the Gateway balloon-Wingspan stent system with a high rate of technical success and acceptable periprocedural morbidity. Our initial experience indicates that this procedure represents a viable treatment option for this patient population.

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Mesh:

Year:  2007        PMID: 17290030     DOI: 10.1161/01.STR.0000257963.65728.e8

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  100 in total

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7.  Influence of patient age and stenosis location on wingspan in-stent restenosis.

Authors:  A S Turk; E I Levy; F C Albuquerque; G L Pride; H Woo; B G Welch; D B Niemann; P D Purdy; B Aagaard-Kienitz; P A Rasmussen; L N Hopkins; T J Masaryk; C G McDougall; D Fiorella
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10.  Normalization of cerebral vasoreactivity using BOLD MRI after intravascular stenting.

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