Literature DB >> 17289382

Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers.

Ozden Ozel Güven1, Taner Erdoğan, Hakan Göker, Sulhiye Yildiz.   

Abstract

In this study, a series of novel phenyl- and benzimidazole-substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Escherichia coli, Candida albicans, and Candida krusei. Compound 6g exhibited the most potent antibacterial activity with lowest MIC values of 3.12 and 6.25 microg/mL against S. aureus and MRSA, respectively.

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Year:  2007        PMID： 17289382     DOI： 10.1016/j.bmcl.2007.01.061

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  27 in total

1.  1-[2-(4-Chloro-benz-yloxy)-2-phenyl-ethyl]-1H-benzotriazole.

Authors:  Ozden Ozel Güven; Meral Bayraktar; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-05-08

2.  1-[2-(2,4-Dichloro-benz-yloxy)-2-phenyl-ethyl]-1H-1,2,4-triazole.

Authors:  Ozden Ozel Güven; Hakan Tahtacı; M Nawaz Tahir; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-11-29

3.  1-[2-(2,4-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-1,2,4-triazole.

Authors:  Ozden Ozel Güven; Hakan Tahtacı; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-10-28

4.  4-(1H-Benzimidazol-2-ylmeth-yl)-2H-1,4-benzothia-zin-3(4H)-one.

Authors:  Hoong-Kun Fun; Mohd Mustaqim Rosli; Janardhana Gowda; A M A Khader; B Kalluraya
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-05-29

5.  1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-benzimidazole.

Authors:  Ozden Ozel Güven; Taner Erdoğan; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-07-09

6.  2-(1H-Benzimidazol-1-yl)-1-phenyl-ethanone.

Authors:  Ozden Ozel Güven; Taner Erdoğan; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-06-28

7.  1-[2-(4-Bromo-benz-yloxy)-2-phenyl-ethyl]-1H-1,2,4-triazole.

Authors:  Ozden Ozel Güven; Hakan Tahtacı; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-09-13

8.  1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-1,2,4-triazole.

Authors:  Ozden Ozel Güven; Hakan Tahtacı; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-12-12

9.  1-{2-Phenyl-2-[4-(trifluoro-meth-yl)-benzyl-oxy]eth-yl}-1H-benzimidazole.

Authors:  Ozden Ozel Güven; Taner Erdoğan; Simon J Coles; Tuncer Hökelek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-07-31

10.  New (3-(1H-benzo[d]imidazol-2-yl))/(3-(3H-imidazo[4,5-b]pyridin-2-yl))-(1H-indol-5-yl)(3,4,5-trimethoxyphenyl)methanone conjugates as tubulin polymerization inhibitors.

Authors:  Kishore Mullagiri; V Lakshma Nayak; Satish Sunkari; Geeta Sai Mani; Sravanthi Devi Guggilapu; Burri Nagaraju; Abdullah Alarifi; Ahmed Kamal
Journal:  Medchemcomm       Date:  2017-12-12       Impact factor: 3.597
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