Literature DB >> 17288482

Simplified synthesis of 3-(1-arylsulfonylalkyl) indoles and their reaction with Reformatsky reagents.

Alessandro Palmieri1, Marino Petrini.   

Abstract

A simple procedure for the preparation of 3-(1-arylsulfonyl-alkyl) indoles by three-component condensation of indoles, carbonyls, and arenesulfinic acids is presented. The obtained products undergo a Reformatsky reaction leading to alkyl 3-(3-indolyl) alkanoates and (3-indolyl) ketones.

Entities:  

Year:  2007        PMID： 17288482     DOI： 10.1021/jo062538e

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

1.  Chiral Brønsted base-promoted nitroalkane alkylation: enantioselective synthesis of sec-alkyl-3-substituted indoles.

Authors:  Mark C Dobish; Jeffrey N Johnston
Journal:  Org Lett       Date:  2010-11-19       Impact factor: 6.005

2.  Direct organocatalytic coupling of carboxylated piperazine-2,5-diones with indoles through conjugate addition of carbon nucleophiles to indolenine intermediates.

Authors:  Ramin Dubey; Bogdan Olenyuk
Journal:  Tetrahedron Lett       Date:  2010-01-27       Impact factor: 2.415

Review 3.  Recent metal-catalysed approaches for the synthesis of cyclopenta[b]indoles.

Authors:  Thavaraj Vivekanand; Bishnupada Satpathi; Siddheshwar K Bankar; S S V Ramasastry
Journal:  RSC Adv       Date:  2018-05-22       Impact factor: 4.036

Review 4.  Arenesulfonyl indole: new precursor for diversification of C-3 functionalized indoles.

Authors:  Banni Preet Kaur; Jasneet Kaur; Swapandeep Singh Chimni
Journal:  RSC Adv       Date:  2021-01-08       Impact factor: 3.361
  4 in total

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