| Literature DB >> 17288390 |
Dhevalapally B Ramachary1, Kinthada Ramakumar, Vidadala V Narayana.
Abstract
A practical and novel one-pot organocatalytic selective process for the cascade synthesis of highly substituted o-hydroxydiarylamines and o-pyrrolidin-1-yldiarylamines is reported. Direct combination of amine-catalyzed cascade Knoevenagel/Michael/aldol condensation/decarboxylation and cascade enamine amination/isoaromatization of alkyl acetoacetates, aldehydes, and nitrosoarenes furnished the highly functionalized anilines with high yields.Entities:
Year: 2007 PMID： 17288390 DOI： 10.1021/jo0623639
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354