Literature DB >> 17288254

[Changes of some energy exchange parameters in the rat heart under insulin hypoglycemia].

P P Potapov, A Iu Stel'makh, P K Telushkin, N B Medvedeva.   

Abstract

Hypoglycemic coma induced by administration of a large dose of insulin, was accompanied by the increased rates of glycolysis, glycogenolysis, activity of lactate dehydrogenase, succinate dehydrogenase, isocitrate dehydrogenase, and increased concentration of glycogen. Under these conditions triacylglycerol content decreased administration of the large dose of insulin to rats with alloxan diabetes increased not only rates of glycolysis, glycogenolysis and lactate dehydrogenase activity and also activities of aspartate transaminase and glutamate dehydrogenase. Data obtained suggest the increased utilization of amino acids for energy supply of myocardium under conditions of hypoglycemia induced by insulin adminisration to diabetic animals.

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Year:  2006        PMID: 17288254

Source DB:  PubMed          Journal:  Biomed Khim        ISSN: 2310-6905


  1 in total

1.  The Contractility of Isolated Rat Atrial Tissue during Hypoxia is Better Preserved in a High- or Zero-Glucose Environment than in a Normal Glucose Environment.

Authors:  Zoltán Szabó; Kristofer Katkits; George Gabro; Rolf Gg Andersson
Journal:  Int J Biomed Sci       Date:  2009-03
  1 in total

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