Literature DB >> 17285389

Continuous perioperative insulin infusion therapy for patients with type 2 diabetes undergoing bariatric surgery.

R Blackstone1, J Kieran, M Davis, L Rivera.   

Abstract

BACKGROUND: Continuous insulin infusion (CII) is proven to decrease morbidity and mortality in surgical critical care patients. This study compared standard insulin therapy with CII in type 2 diabetes patients undergoing elective bariatric surgical procedures in a community hospital.
METHODS: A retrospective review investigated 350 bariatric surgical patients with type 2 diabetes who underwent perioperative treatment of hyperglycemia using either standard insulin therapy or CII. The 182 patients in group 1 underwent glucose monitoring and subcutaneous insulin treatment every 6 h, whereas the 168 patients in group 2 had CII treatment beginning in the preoperative holding area and monitored hourly for the next 24 h. The two groups were similar in demographic characteristics.
RESULTS: There were no significant hypoglycemic episodes with perioperative CII. The mean perioperative insulin required was 5.8 U/h. The patients receiving CII had fewer postprocedure cholecystectomies, but a higher number of port-site infections.
CONCLUSIONS: Perioperative CII can be administered safely to diabetic patients undergoing bariatric surgery. The insulin requirements in this population are higher than expected. Our study showed a decrease in the number of postoperative cholecystectomies in the CII group, but no effect on the stricture rate and an increase in the number of patients with postoperative port-site infections.

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Year:  2007        PMID: 17285389     DOI: 10.1007/s00464-006-9100-0

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  28 in total

1.  Effect of BMI, insulin dose and number of injections on glycaemic control in insulin-using diabetic patients. Studygroup Diabetes Rijnmond (SDR).

Authors:  M L Jacobs; J W Elte; B M van Ouwerkerk; E N Janssens; C Schop; J A Knoop; R P Hoogma; R Groenendijk; R F Weber
Journal:  Neth J Med       Date:  1997-04       Impact factor: 1.422

2.  Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels.

Authors:  Troels Krarup Hansen; Steffen Thiel; Pieter Jozef Wouters; Jens Sandahl Christiansen; Greet Van den Berghe
Journal:  J Clin Endocrinol Metab       Date:  2003-03       Impact factor: 5.958

3.  Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures.

Authors:  A P Furnary; K J Zerr; G L Grunkemeier; A Starr
Journal:  Ann Thorac Surg       Date:  1999-02       Impact factor: 4.330

4.  Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients.

Authors:  Ilse Vanhorebeek; Rita De Vos; Dieter Mesotten; Pieter J Wouters; Christiane De Wolf-Peeters; Greet Van den Berghe
Journal:  Lancet       Date:  2005 Jan 1-7       Impact factor: 79.321

5.  Continuous subcutaneous insulin infusion in type 1 diabetic Saudi children. A comparison with conventional insulin therapy.

Authors:  Bassam S Bin-Abbas; Nadia A Sakati; Hussein Raef; Abdullah A Al-Ashwal
Journal:  Saudi Med J       Date:  2005-06       Impact factor: 1.484

Review 6.  The role of intensive glycemic control in the management of patients who have acute myocardial infarction.

Authors:  Stuart W Zarich
Journal:  Cardiol Clin       Date:  2005-05       Impact factor: 2.213

7.  Effect of hyperglycemia and continuous intravenous insulin infusions on outcomes of cardiac surgical procedures: the Portland Diabetic Project.

Authors:  Anthony P Furnary; YingXing Wu; Stephen O Bookin
Journal:  Endocr Pract       Date:  2004 Mar-Apr       Impact factor: 3.443

8.  Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting.

Authors:  Anthony P Furnary; Guangqiang Gao; Gary L Grunkemeier; YingXing Wu; Kathryn J Zerr; Stephen O Bookin; H Storm Floten; Albert Starr
Journal:  J Thorac Cardiovasc Surg       Date:  2003-05       Impact factor: 5.209

Review 9.  Bariatric surgery: a systematic review and meta-analysis.

Authors:  Henry Buchwald; Yoav Avidor; Eugene Braunwald; Michael D Jensen; Walter Pories; Kyle Fahrbach; Karen Schoelles
Journal:  JAMA       Date:  2004-10-13       Impact factor: 56.272

10.  Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy.

Authors:  Dieter Mesotten; Johannes V Swinnen; Frank Vanderhoydonc; Pieter J Wouters; Greet Van den Berghe
Journal:  J Clin Endocrinol Metab       Date:  2004-01       Impact factor: 5.958

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