| Literature DB >> 17285108 |
T V Bagnyukova1, I P Pogribny, V F Chekhun.
Abstract
MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression at posttranscriptional level. They are involved in cellular development, differentiation, proliferation and apoptosis and play a significant role in cancer. This review describes miRNA biogenesis, their functions in normal cells, and alterations of miRNA sets in cancer and roles of antitumorigenic and oncogenic miRNAs in cancer development.Entities:
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Year: 2006 PMID: 17285108
Source DB: PubMed Journal: Exp Oncol ISSN: 1812-9269