Literature DB >> 17284986

Aortic valve replacement in elderly patients: what are the limits?

Lawrence H Cohn1, Narendren Narayanasamy.   

Abstract

PURPOSE OF REVIEW: Increased life expectancy has led to a growing elderly population frequently presenting with aortic stenosis. This review focuses on modalities of aortic valve replacement designed to cope with the risks from multiple co-morbidities prevalent in the elderly. RECENT
FINDINGS: Cardiac surgery is safe in octogenarians; very low risks are associated with aortic valve replacement. Good short-term and medium-term results are seen with early surgical intervention for aortic stenosis in the relatively asymptomatic patient. The benefits seen with minimally invasive surgery make it more acceptable. A hybrid approach that deploys a drug-eluting stent for concomitant moderate coronary artery disease has shown promising results. An extension of this concept is the percutaneous aortic valve implantation that offers hope to the nonsurgical candidate. A systematic approach of minimally invasive surgery in patients with prior coronary artery bypass grafting minimizes injury to grafts. Bioprosthetic tissue valves are the valves of choice in all the above interventions.
SUMMARY: Cardiac surgery is used increasingly for aortic stenosis in elderly patients. Current experiences in minimally invasive and percutaneous approaches have opened the doors to hybrid strategies, which may be the mainstay of treatment for older patients needing aortic valve replacements in the future.

Entities:  

Mesh:

Year:  2007        PMID: 17284986     DOI: 10.1097/HCO.0b013e32802086bc

Source DB:  PubMed          Journal:  Curr Opin Cardiol        ISSN: 0268-4705            Impact factor:   2.161


  3 in total

1.  Endothelial differentiation of adipose-derived stem cells from elderly patients with cardiovascular disease.

Authors:  Ping Zhang; Neil Moudgill; Eric Hager; Nicolas Tarola; Christopher Dimatteo; Stephen McIlhenny; Thomas Tulenko; Paul J DiMuzio
Journal:  Stem Cells Dev       Date:  2010-11-01       Impact factor: 3.272

2.  Trends in aortic valve replacement for elderly patients in the United States, 1999-2011.

Authors:  José Augusto Barreto-Filho; Yun Wang; John A Dodson; Mayur M Desai; Lissa Sugeng; Arnar Geirsson; Harlan M Krumholz
Journal:  JAMA       Date:  2013-11-20       Impact factor: 56.272

Review 3.  The evolution of cardiovascular surgery in elderly patient: a review of current options and outcomes.

Authors:  Francesco Nicolini; Andrea Agostinelli; Antonella Vezzani; Tullio Manca; Filippo Benassi; Alberto Molardi; Tiziano Gherli
Journal:  Biomed Res Int       Date:  2014-04-10       Impact factor: 3.411

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.