Literature DB >> 17284072

Myriaporones 1-4, cytotoxic metabolites from the Mediterranean bryozoan Myriapora truncata.

Jie-Fei Cheng1, Jong-Soo Lee, Ryuichi Sakai, Elizabeth A Jares-Erijman, Maria V Silva, Kenneth L Rinehart.   

Abstract

Four novel polyketide-derived metabolites, myriaporones 1, 2, 3, and 4, have been isolated from the Mediterranean bryozoan Myriapora truncata. Their structures and stereochemistry have been assigned from the analysis of spectroscopic data. The inseparable equilibrium mixture of myriaporones 3 and 4 showed 88% inhibition of L1210 murine leukemia cells at 0.2 microg/mL.

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Year:  2007        PMID： 17284072     DOI： 10.1021/np060308p

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  New candidaspongiolides, tedanolide analogues that selectively inhibit melanoma cell growth.

Authors:  Emily L Whitson; Kristen M Pluchino; Matthew D Hall; James B McMahon; Tawnya C McKee
Journal:  Org Lett       Date:  2011-06-06       Impact factor: 6.005

2.  Molecular Basis for Olefin Rearrangement in the Gephyronic Acid Polyketide Synthase.

Authors:  Greg J Dodge; Danialle Ronnow; Richard E Taylor; Janet L Smith
Journal:  ACS Chem Biol       Date:  2018-09-12       Impact factor: 5.100

3.  Smardaesidins A-G, isopimarane and 20-nor-isopimarane diterpenoids from Smardaea sp., a fungal endophyte of the moss Ceratodon purpureus.

Authors:  Xiao-Ning Wang; Bharat P Bashyal; E M Kithsiri Wijeratne; Jana M U'Ren; Manping X Liu; Malkanthi K Gunatilaka; A Elizabeth Arnold; A A Leslie Gunatilaka
Journal:  J Nat Prod       Date:  2011-10-14       Impact factor: 4.050

4.  18O assisted analysis of a γ,δ-epoxyketone cyclization: synthesis of the C16-C28 fragment of ammocidin D.

Authors:  Stephen T Chau; Yoichi Hayakawa; Gary A Sulikowski
Journal:  Org Lett       Date:  2011-01-19       Impact factor: 6.005

5.  Plakortinic Acids A and B: Cytotoxic Cycloperoxides with a Bicyclo[4.2.0]octene Unit from Sponges of the Genera Plakortis and Xestospongia.

Authors:  Carlos Jiménez-Romero; Abimael D Rodríguez; Sangkil Nam
Journal:  Org Lett       Date:  2017-03-08       Impact factor: 6.072

Review 6.  The Phylum Bryozoa as a Promising Source of Anticancer Drugs.

Authors:  Blanca Figuerola; Conxita Avila
Journal:  Mar Drugs       Date:  2019-08-17       Impact factor: 5.118
  6 in total

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