Literature DB >> 17284033

Carbocyclization by radical closure onto O-trityl oximes: dramatic effect of diphenyl diselenide.

Derrick L J Clive1, Mai P Pham, Rajendra Subedi.   

Abstract

O-Trityl oximes of 5- and 6-iodoaldehydes undergo radical cyclization to produce oximes when treated in refluxing tetrahydrofuran (THF) with Bu3SnH, 1,1'-azobis(cyclohexanecarbonitrile), i-Pr2NEt, and diphenyl diselenide (PhSeSePh).

Entities:  

Year:  2007        PMID: 17284033     DOI: 10.1021/ja067117t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  1 in total

1.  Diastereoselective synthesis of cyclopentapyridazinones via radical cyclization: synthetic studies toward halichlorine.

Authors:  Gary E Keck; Stacey A Heumann
Journal:  Org Lett       Date:  2008-09-25       Impact factor: 6.005

  1 in total

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