Literature DB >> 17283111

Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells.

Evelyn Ullrich1, Mathieu Bonmort, Grégoire Mignot, Nathalie Chaput, Julien Taieb, Cédric Ménard, Sophie Viaud, Thomas Tursz, Guido Kroemer, Laurence Zitvogel.   

Abstract

A unique class of IFN-producing killer dendritic cells (IKDC) resembling natural killer cells has been defined that can recognize and lyse tumor cells through a tumor necrosis factor-related apoptosis-inducing ligand-dependent mechanism. IKDC may mediate the host-dependent antitumor activity of Gleevec/STI571 and other therapeutics that can inhibit the c-kit tyrosine kinase. IKDC represent an important new component of the innate immune system responding to cancer.

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Year:  2007        PMID： 17283111     DOI： 10.1158/0008-5472.CAN-06-3766

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  6 in total

1.  Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells.

Authors:  Kerstin A Sauer; Joachim H Maxeiner; Roman Karwot; Petra Scholtes; Hans A Lehr; Mark Birkenbach; Richard S Blumberg; Susetta Finotto
Journal:  J Immunol       Date:  2008-11-01       Impact factor: 5.422

Review 2.  Noncanonical roles of the immune system in eliciting oncogene addiction.

Authors:  Stephanie C Casey; David I Bellovin; Dean W Felsher
Journal:  Curr Opin Immunol       Date:  2013-04-06       Impact factor: 7.486

Review 3.  Dendritic cell tumor killing activity and its potential applications in cancer immunotherapy.

Authors:  Neale Hanke; Darya Alizadeh; Emmanuel Katsanis; Nicolas Larmonier
Journal:  Crit Rev Immunol       Date:  2013       Impact factor: 2.214

4.  A novel recombinant protein of ephrinA1-PE38/GM-CSF activate dendritic cells vaccine in rats with glioma.

Authors:  Ming Li; Bin Wang; Zhonghua Wu; Jiadong Zhang; Xiwen Shi; Wenlan Cheng; Shuangyin Han
Journal:  Tumour Biol       Date:  2015-02-13

5.  Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines.

Authors:  Denise L Driscoll; Arijit Chakravarty; Doug Bowman; Vaishali Shinde; Kerri Lasky; Judy Shi; Tricia Vos; Bradley Stringer; Ben Amidon; Natalie D'Amore; Marc L Hyer
Journal:  PLoS One       Date:  2014-11-03       Impact factor: 3.240

6.  CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells.

Authors:  Christian A J Vosshenrich; Sarah Lesjean-Pottier; Milena Hasan; Odile Richard-Le Goff; Erwan Corcuff; Ofer Mandelboim; James P Di Santo
Journal:  J Exp Med       Date:  2007-10-08       Impact factor: 14.307
  6 in total

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