| Literature DB >> 17280587 |
L Bueno1, F de Ponti, M Fried, G A Kullak-Ublick, M A Kwiatek, D Pohl, E M M Quigley, J Tack, N J Talley.
Abstract
Visceral hypersensitivity is considered a key mechanism in the pathogenesis of functional gastrointestinal (GI) disorders. Targeting visceral hypersensitivity seems an attractive approach to the development of drugs for functional GI disorders. This review summarizes current knowledge on targets for the treatment of visceral hypersensitivity, and the status of current and future drug and probiotic treatment development, and the role of pharmacogenomic factors.Entities:
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Year: 2007 PMID: 17280587 DOI: 10.1111/j.1365-2982.2006.00876.x
Source DB: PubMed Journal: Neurogastroenterol Motil ISSN: 1350-1925 Impact factor: 3.598