Literature DB >> 17279762

Solid-phase synthesis and on-column deprotection of RNA from 2'- (and 3'-) O-levulinated (Lv) ribonucleoside monomers.

Jeremy G Lackey1, David Sabatino, Masad J Damha.   

Abstract

[reaction: see text] The solid-phase synthesis of oligoribonucleotides derived from ribonucleosides esterified at the 2'- (or 3'-) position with the levulinyl (Lv) group is described. The oligomers can be released from the solid support as 2'-O-Lv ester derivatives or fully deprotected while still attached to the solid support.

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Year:  2007        PMID： 17279762     DOI： 10.1021/ol0629521

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation.

Authors:  Heather P Harding; Jeremy G Lackey; Hao-Chi Hsu; Yuhong Zhang; Jing Deng; Rui-Ming Xu; Masad J Damha; David Ron
Journal:  RNA       Date:  2007-12-19       Impact factor: 4.942

Review 2.  Spotting, Transcription and In Situ Synthesis: Three Routes for the Fabrication of RNA Microarrays.

Authors:  Jory Lietard; Mark M Somoza
Journal:  Comput Struct Biotechnol J       Date:  2019-06-27       Impact factor: 7.271

3.  Solid-phase synthesis and hybrization behavior of partially 2'/3'-O-acetylated RNA oligonucleotides.

Authors:  Jianfeng Xu; Colm D Duffy; Christopher K W Chan; John D Sutherland
Journal:  J Org Chem       Date:  2014-03-31       Impact factor: 4.354

4.  High-Density RNA Microarrays Synthesized In Situ by Photolithography.

Authors:  Jory Lietard; Dominik Ameur; Masad J Damha; Mark M Somoza
Journal:  Angew Chem Int Ed Engl       Date:  2018-10-19       Impact factor: 15.336
  4 in total

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