Literature DB >> 17278816

Investigations of different kilovoltage X-ray energy for three-dimensional converging stereotactic radiotherapy system: Monte Carlo simulations with CT data.

Hossain M Deloar1, Etsuo Kunieda, Takatsugu Kawase, Takanori Tsunoo, Hidetoshi Saitoh, Masahiro Ozaki, Kimiaki Saito, Shunji Takagi, Osamu Sato, Tatsuya Fujisaki, Atsushi Myojoyama, Graham Sorell.   

Abstract

We are investigating three-dimensional converging stereotactic radiotherapy (3DCSRT) with suitable medium-energy x rays as treatment for small lung tumors with better dose homogeneity at the target. A computed tomography (CT) system dedicated for non-coplanar converging radiotherapy was simulated with BEAMnrc (EGS4) Monte-Carlo code for x-ray energy of 147.5, 200, 300, and 500 kilovoltage (kVp). The system was validated by comparing calculated and measured percentage of depth dose in a water phantom for the energy of 120 and 147.5 kVp. A thorax phantom and CT data from lung tumors (<20 cm3) were used to compare dose homogeneities of kVp energies with MV energies of 4, 6, and 10 MV. Three non-coplanar arcs (0 degrees and +/-25 degrees ) around the center of the target were employed. The Monte Carlo dose data format was converted to the XiO RTP format to compare dose homogeneity, differential, and integral dose volume histograms of kVp and MV energies. In terms of dose homogeneity and DVHs, dose distributions at the target of all kVp energies with the thorax phantom were better than MV energies, with mean dose absorption at the ribs (human data) of 100%, 85%, 50%, 30% for 147.5, 200, 300, and 500 kVp, respectively. Considering dose distributions and reduction of the enhanced dose absorption at the ribs, a minimum of 500 kVp is suitable for the lung kVp 3DCSRT system.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 17278816     DOI: 10.1118/1.2361080

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  1 in total

1.  Monte carlo simulation of an X-ray pixel beam microirradiation system.

Authors:  E C Schreiber; S X Chang
Journal:  Radiat Res       Date:  2009-03       Impact factor: 2.841

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.