| Literature DB >> 17276350 |
Abstract
GCN2 is a sensor of amino acid deprivation that triggers a repression of global protein synthesis while simultaneously inducing translation of specific proteins. In this issue of Cell Metabolism, Guo and Cavener (2007) present a much broader role for GCN2 in controlling lipid homeostasis in response to amino acid deprivation.Entities:
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Year: 2007 PMID: 17276350 DOI: 10.1016/j.cmet.2007.01.010
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287