| Literature DB >> 17276348 |
Abstract
In this issue of Cell Metabolism, Espenshade and colleagues (Hughes et al., 2007) show that the hemoprotein Dap1/PGRMC1 forms a stable complex with several members of the cytochrome P450 superfamily of enzymes and positively regulates their activities. This action indicates an important role for Dap1/PGRMC1 in P450-catalyzed reactions, some of which are involved in the metabolism of sterols and pharmaceutical compounds.Entities:
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Year: 2007 PMID： 17276348 DOI： 10.1016/j.cmet.2007.01.007
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287