| Literature DB >> 17276335 |
Myriam Hemberger1, Wendy Dean.
Abstract
Epigenetic modifications of nucleosomal histones are thought to mediate transcriptional states and impose heritable instructions upon differentiation. In a paper of Torres-Padilla and colleagues in Nature, protein modification at arginine residues, namely of core histones, is correlated with cell fate determination at the 4-cell stage in the mouse embryo. This represents the first link of global epigenetic instructions associated with specification of early cell lineages.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17276335 DOI： 10.1016/j.devcel.2006.12.004
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270