Literature DB >> 17275980

Applications of Botulinum toxin in urogynaecology.

D Sinha1, K Karri, A S Arunkalaivanan.   

Abstract

Botulinum toxin (BTX) is a neurotoxin produced by bacterium clostridium. It is the most poisonous naturally occurring substance known to mankind. The neurotoxin binds to the peripheral cholinergic terminals and inhibits acetylcholine release at that junction leading to flaccid paralysis. This process appears to offer an attractive therapeutic option, filling the void between anticholinergics and surgery in cases of neurogenic and idiopathic detrusor overactivity, detrusor sphincter dyssynergia (DSD), interstitial cystitis and pelvic pain. This article reviews the application of Botulinum toxin A in these conditions.

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Year:  2007        PMID： 17275980     DOI： 10.1016/j.ejogrb.2006.12.014

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN： 0301-2115            Impact factor:   2.435


  4 in total

1.  Detection of botulinum neurotoxin serotype A, B, and F proteolytic activity in complex matrices with picomolar to femtomolar sensitivity.

Authors:  F Mark Dunning; Daniel R Ruge; Timothy M Piazza; Larry H Stanker; Füsûn N Zeytin; Ward C Tucker
Journal:  Appl Environ Microbiol       Date:  2012-08-24       Impact factor: 4.792

2.  Isolation and quantification of botulinum neurotoxin from complex matrices using the BoTest matrix assays.

Authors:  F Mark Dunning; Timothy M Piazza; Füsûn N Zeytin; Ward C Tucker
Journal:  J Vis Exp       Date:  2014-03-03       Impact factor: 1.355

3.  Effect of Acupuncture on Chronic Pelvic Pain Secondary to Abdominal Myofascial Syndrome Not Responsive to Local Anesthetic Block: A Pilot Study.

Authors:  Andréia Moreira de Souza Mitidieri; Maria Beatriz Ferreira Gurian; Ana Paula Moreira da Silva; Omero Benedicto Poli-Neto; Antônio Alberto Nogueira; Francisco José Candido-Dos-Reis; Júlio César Rosa-E-Silva
Journal:  Med Acupunct       Date:  2017-12-01

Review 4.  The efficacy of botulinum toxin a injections in pelvic floor muscles in chronic pelvic pain patients: a systematic review and meta-analysis.

Authors:  Melle A Spruijt; Wenche M Klerkx; Johannes C Kelder; Kirsten B Kluivers; Manon H Kerkhof
Journal:  Int Urogynecol J       Date:  2022-04-01       Impact factor: 1.932
  4 in total

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