Literature DB >> 17274854

An epidemiological investigation of affective disorders with a population-based cohort of 1023 adults with intellectual disabilities.

Sally-Ann Cooper1, Elita Smiley, Jillian Morrison, Andrew Williamson, Linda Allan.   

Abstract

BACKGROUND: Intellectual disabilities (ID) are common and lifelong. People with ID have health inequalities compared with the general population, but little is known about the epidemiology of affective disorders in this population. This study was undertaken to determine the point prevalence of affective disorders, and to investigate factors associated with depression.
METHOD: This population-based study (n=1023) included comprehensive individual assessments with each person. A two-stage process was used for diagnosis of affective disorders. Factors independently associated with depression were investigated through logistic regression analysis.
RESULTS: The point prevalence was higher than that reported previously for the general population; DC-LD yielded 3.8% for depression and 0.6% for mania. Additionally, 1.0% had bipolar disorder currently in remission, and 0.1% first episode of mania currently in remission. Similar to general population findings, depression was associated with female gender, smoking, number of preceding family physician appointments, and preceding life events. Important differences were the association of not having a hearing impairment, and the trends for not living in deprived areas, and being married. Unlike general population findings, not having daytime occupation and obesity were not independently associated; nor was previous long-stay hospital residence, severity of ID, or sensory impairments.
CONCLUSIONS: This study has found a high point prevalence of affective disorders in adults with ID. The factors associated with depression have differences to general population findings. An understanding of this is important in order to develop appropriate interventions, public strategy and policy, to reduce existing health inequalities.

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Mesh:

Year:  2007        PMID: 17274854     DOI: 10.1017/S0033291707009968

Source DB:  PubMed          Journal:  Psychol Med        ISSN: 0033-2917            Impact factor:   7.723


  15 in total

Review 1.  Screening tests for adults with intellectual disabilities.

Authors:  Joanne E Wilkinson; Larry Culpepper; Mary Cerreto
Journal:  J Am Board Fam Med       Date:  2007 Jul-Aug       Impact factor: 2.657

2.  The prevalence and incidence of mental ill-health in adults with autism and intellectual disabilities.

Authors:  Craig A Melville; Sally-Ann Cooper; Jill Morrison; Elita Smiley; Linda Allan; Alison Jackson; Janet Finlayson; Dipali Mantry
Journal:  J Autism Dev Disord       Date:  2008-02-29

3.  Cognitive Behavioral Therapy for Depressed Adults with Mild Intellectual Disability: A Pilot Study.

Authors:  Sigan L Hartley; Anna J Esbensen; Rebecca Shalev; Lori B Vincent; Iulia Mihaila; Paige Bussanich
Journal:  J Ment Health Res Intellect Disabil       Date:  2015-04-06

4.  "Intellectual developmental disorders": reflections on the international consensus document for redefining "mental retardation-intellectual disability" in ICD-11.

Authors:  Marco O Bertelli; Kerim Munir; James Harris; Luis Salvador-Carulla
Journal:  Adv Ment Health Intellect Disabil       Date:  2016

5.  Depression in adults with mild intellectual disability: role of stress, attributions, and coping.

Authors:  Sigan L Hartley; William E Maclean
Journal:  Am J Intellect Dev Disabil       Date:  2009-05

6.  Reassurance seeking and depression in adults with mild intellectual disability.

Authors:  S L Hartley; A Hayes Lickel; W E MacLean
Journal:  J Intellect Disabil Res       Date:  2008-11

7.  Nonverbal Social Skills of Adults with Mild Intellectual Disability Diagnosed with Depression.

Authors:  Sigan L Hartley; Denis Birgenheir
Journal:  J Ment Health Res Intellect Disabil       Date:  2009-01-01

8.  Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex.

Authors:  Minghui Wang; Nicholas B Gallo; Yilin Tai; Bo Li; Linda Van Aelst
Journal:  Neuron       Date:  2021-04-07       Impact factor: 18.688

9.  Characterizing Mood States in Individuals Diagnosed with Bipolar Disorder and Intellectual Disability.

Authors:  Maria G Valdovinos; Haley N Seibert; Drew Piersma; Alyssa Wilkinson; Gabrielle Griffith; Sara Hillring; Bailey Boyle
Journal:  J Ment Health Res Intellect Disabil       Date:  2019-03-01

10.  Mental illness, challenging behaviour, and psychotropic drug prescribing in people with intellectual disability: UK population based cohort study.

Authors:  Rory Sheehan; Angela Hassiotis; Kate Walters; David Osborn; André Strydom; Laura Horsfall
Journal:  BMJ       Date:  2015-09-01
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