Literature DB >> 17273943

Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.

Gary D Kruh1, Martin G Belinsky, James M Gallo, Kun Lee.   

Abstract

The MRP family is composed of nine transporters, at least eight of which are lipophilic anion transporters that are capable of conferring resistance to various anticancer agents. Recently, mice with gene disruptions in Mrp2, Mrp3 and Mrp4 have been developed. This review will discuss insights into the physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 afforded by investigations of these new mouse models.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17273943     DOI： 10.1007/s10555-007-9039-1

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  25 in total

Review 1.  Chemotherapy and signaling: How can targeted therapies supercharge cytotoxic agents?

Authors:  Tetyana V Bagnyukova; Ilya G Serebriiskii; Yan Zhou; Elizabeth A Hopper-Borge; Erica A Golemis; Igor Astsaturov
Journal:  Cancer Biol Ther       Date:  2010-11-01       Impact factor: 4.742

2.  PharmGKB summary: methotrexate pathway.

Authors:  Torben S Mikkelsen; Caroline F Thorn; Jun J Yang; Cornelia M Ulrich; Deborah French; Gianluigi Zaza; Henry M Dunnenberger; Sharon Marsh; Howard L McLeod; Kathy Giacomini; Mara L Becker; Roger Gaedigk; James Steven Leeder; Leo Kager; Mary V Relling; William Evans; Teri E Klein; Russ B Altman
Journal:  Pharmacogenet Genomics       Date:  2011-10       Impact factor: 2.089

Review 3.  Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases.

Authors:  Zhe-Sheng Chen; Amit K Tiwari
Journal:  FEBS J       Date:  2011-08-01       Impact factor: 5.542

Review 4.  Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis.

Authors:  Carol J Soroka; Nazzareno Ballatori; James L Boyer
Journal:  Semin Liver Dis       Date:  2010-04-26       Impact factor: 6.115

Review 5.  The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.

Authors:  Larry H Matherly; Mike R Wilson; Zhanjun Hou
Journal:  Drug Metab Dispos       Date:  2014-01-06       Impact factor: 3.922

6.  Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells.

Authors:  Stacy L Gelhaus; Oren Gilad; Wei-Ting Hwang; Trevor M Penning; Ian A Blair
Journal:  Toxicol Lett       Date:  2011-11-30       Impact factor: 4.372

7.  Network correlation analysis revealed potential new mechanisms for neural tube defects beyond folic acid.

Authors:  Xiaoya Gao; Richard H Finnell; Hongyan Wang; Yufang Zheng
Journal:  Birth Defects Res       Date:  2018-05-06       Impact factor: 2.344

8.  Citrobacter rodentium Infection Inhibits Colonic P-glycoprotein Expression.

Authors:  Mitul Patel; Anoop Kumar; Dulari Jayawardena; Shubha Priyamvada; Arivarasu N Anbazhagan; Waddah A Alrefai; Ravinder K Gill; Pradeep K Dudeja; Seema Saksena
Journal:  Gene Rep       Date:  2019-10-31

9.  The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.

Authors:  Anuradha Rao; Jamie Haywood; Ann L Craddock; Martin G Belinsky; Gary D Kruh; Paul A Dawson
Journal:  Proc Natl Acad Sci U S A       Date:  2008-02-21       Impact factor: 11.205

Review 10.  Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology.

Authors:  Nazzareno Ballatori; Suzanne M Krance; Rosemarie Marchan; Christine L Hammond
Journal:  Mol Aspects Med       Date:  2008-08-26
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.