| Literature DB >> 17272837 |
Sonia Longhi1, François Ferron, Marie-Pierre Egloff.
Abstract
This chapter focuses on protein engineering strategies that aim to increase the chances of obtaining crystals suitable for X-ray diffraction. The chapter is divided into three main parts: one dealing with protein engineering through a bioinformatics approach, the second focusing on DNA modifications via random mutagenesis, and the third describing a nonexhaustive number of in vitro modifications based on site-directed mutagenesis.Mesh：
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Year: 2007 PMID： 17272837 DOI： 10.1007/978-1-59745-209-0_4
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745