OBJECTIVE: The authors report on the relationship between cognitive functioning and instrumental activities of daily living (IADLs) in elderly, clinically euthymic adults with bipolar disorder. METHODS: Twenty patients with bipolar disorder (age range: 61-86 years) were administered comprehensive neuropsychologic testing. Structured in-home performance-based assessments of IADLs were performed in 19 of these patients. RESULTS: Relative to age-equated comparators, bipolar subjects performed worse in information-processing speed and executive functioning. IADL performance was strongly correlated with these cognitive domains. CONCLUSIONS: In euthymic elderly patients with bipolar disorder, decrements in information processing speed and executive functioning characterize cognitive function and are associated with poorer IADL performance.
OBJECTIVE: The authors report on the relationship between cognitive functioning and instrumental activities of daily living (IADLs) in elderly, clinically euthymic adults with bipolar disorder. METHODS: Twenty patients with bipolar disorder (age range: 61-86 years) were administered comprehensive neuropsychologic testing. Structured in-home performance-based assessments of IADLs were performed in 19 of these patients. RESULTS: Relative to age-equated comparators, bipolar subjects performed worse in information-processing speed and executive functioning. IADL performance was strongly correlated with these cognitive domains. CONCLUSIONS: In euthymic elderly patients with bipolar disorder, decrements in information processing speed and executive functioning characterize cognitive function and are associated with poorer IADL performance.
Authors: Lynn M Martire; Gregory A Hinrichsen; Jennifer Q Morse; Charles F Reynolds; Ariel G Gildengers; Benoit H Mulsant; Richard Schulz; Ellen Frank; David J Kupfer Journal: Psychiatry Res Date: 2009-05-08 Impact factor: 3.222
Authors: Robert C Young; Benoit H Mulsant; Martha Sajatovic; Ariel G Gildengers; Laszlo Gyulai; Rayan K Al Jurdi; John Beyer; Jovier Evans; Samprit Banerjee; Rebecca Greenberg; Patricia Marino; Mark E Kunik; Peijun Chen; Marna Barrett; Herbert C Schulberg; Martha L Bruce; Charles F Reynolds; George S Alexopoulos Journal: Am J Psychiatry Date: 2017-08-04 Impact factor: 18.112
Authors: Christopher R Bowie; Colin Depp; John A McGrath; Paula Wolyniec; Brent T Mausbach; Mary H Thornquist; James Luke; Thomas L Patterson; Philip D Harvey; Ann E Pulver Journal: Am J Psychiatry Date: 2010-05-17 Impact factor: 18.112
Authors: Ariel G Gildengers; Meryl A Butters; Denise Chisholm; Stewart J Anderson; Amy Begley; Margo Holm; Joan C Rogers; Charles F Reynolds; Benoit H Mulsant Journal: Bipolar Disord Date: 2012-03 Impact factor: 6.744
Authors: Brent T Mausbach; Philip D Harvey; Ann E Pulver; Colin A Depp; Paula S Wolyniec; Mary H Thornquist; James R Luke; John A McGrath; Christopher R Bowie; Thomas L Patterson Journal: Bipolar Disord Date: 2010-02 Impact factor: 6.744
Authors: A G Gildengers; D Chisholm; M A Butters; S J Anderson; A Begley; M Holm; J C Rogers; C F Reynolds; B H Mulsant Journal: Psychol Med Date: 2012-07-30 Impact factor: 7.723
Authors: Ariel G Gildengers; Benoit H Mulsant; Amy Begley; Sati Mazumdar; Adriana V Hyams; Charles F Reynolds Iii; David J Kupfer; Meryl A Butters Journal: Bipolar Disord Date: 2009-08-28 Impact factor: 6.744