Senciltrade mark project: development of a percutaneous optical biosensor.

We describe the design, fabrication method, biocompatibility test results, and first application of the novel chemical sensor technology that is under development. The sensor is designed to be minimally invasive, disposable and easily readable to make frequent measurements of various analytes in vivo over a period of 1-3 months. It uses photonic sensing of a chemical reaction that occurs in a polymer matrix bound to the internal end of a chronically implanted percutaneous optical fiber.