FSH biosensor to detect postpartum ovarian recrudescence.

Preliminary evidence of FSH suppression as a marker of postpartum ovarian recrudescence is presented. Falling FSH concentration in response to ovarian follicular estrogenic secretory activity apparently signals the reestablishment of menstrual cycles. We propose to investigate further this phenomenon with the development of a portable FSH biosensor. The FSH biosensor design is based on SPR and biological thin-film technologies and is incorporated as a key element of the fertility information appliance. It is possible that the device could be a useful natural family planning tool, especially during the return to fertility after childbirth.