Spatio-temporal EEG dipole estimation by means of a hybrid genetic algorithm.

EEG source localization can be considered as a nonlinear optimization process. In the present study, a hybrid genetic algorithm (HGA) is introduced, which combines genetic and local search strategies to overcome the disadvantages of conventional genetic algorithm and local optimization methods. This HGA algorithm was used to localize two dipoles from scalp EEG, and yielded localization accuracy range of 0.95 cm-1.55 cm when the noise level is within 15%, which is better than the Simplex and GA algorithms in localizing multiple dipoles.