| Literature DB >> 17270439 |
Marcin Drag1, Renata Grzywa, Jozef Oleksyszyn.
Abstract
Here we describe the inhibitory activity toward neutral aminopeptidase of three new families of phosphinate inhibitors related in structure to hydroxamic acids. These compounds, even as racemic mixtures, are good inhibitors of APN and show strong structure activity relationship (SAR) depending on the substituents in P1 and P1' positions.Entities:
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Year: 2007 PMID： 17270439 DOI： 10.1016/j.bmcl.2007.01.028
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823