Literature DB >> 17269884

Evaluation of the repeatability of rhinomanometry and its use in assessing transnasal resistance and pressure in dogs.

Thomas S Wiestner1, Daniel A Koch, Natascha Nad, Aaron Balli, Malgorzata Roos, Richard Weilenmann, Erika Michel, Susanna Arnold.   

Abstract

OBJECTIVE: To evaluate a modified posterior rhinomanometric method for clinical application in dogs. ANIMALS: 15 healthy Beagles and 8 Bulldogs (4 healthy and 4 with respiratory problems). PROCEDURES: Rhinomanometry was performed 3 times within a 15-minute period in anesthetized dogs. Transnasal pressure (P(NA)) and nasal resistance (R(NA)) were determined by use of artificial airflow (adjusted for body weight) for inspiration (P(NAin) and R(NAin), respectively) and expiration (P(NAout) and R(NAout)). Procedures were repeated for the Beagles 7 days later.
RESULTS: For the Beagles, mean +/- SD of P(NAin) for both days (0.162 +/- 0.042 kPa) was significantly lower than P(NAout) (0.183 +/- 0.053 kPa). Similarly, R(NAin) (1.47 +/- 0.41 kPa/[L/s]) was significantly lower than R(NAout) (1.64 +/- 0.46 kPa/[L/s]). Pairwise comparison of values for P(NA) and R(NA) for the 2 days revealed no significant difference. Repeatability of the method (estimated as within-day variation) for R(NA) was +/- 0.19 kPa/(L/s), whereas variation between the days was +/- 0.36 kPa/(L/s) for R(NAin) and +/- 0.44 kPa/(L/s) for R(NAout). The 4 clinically normal Bulldogs had R(NA) values ranging from 1.69 to 3.48 kPa/(L/s), whereas in the 4 Bulldogs with respiratory problems, R(NA) ranged from 9.83 to 20.27 kPa/(L/s). CONCLUSIONS AND CLINICAL RELEVANCE: R(NA) is inversely dependent on body size and nonlinearly associated with airflow. We propose that R(NA) in dogs should be determined for airflows standardized on the basis of body size. The P(NA) and R(NA) in Beagles can be measured with sufficient repeatability for clinical use and nasal obstructions are detectable.

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Year:  2007        PMID: 17269884     DOI: 10.2460/ajvr.68.2.178

Source DB:  PubMed          Journal:  Am J Vet Res        ISSN: 0002-9645            Impact factor:   1.156


  2 in total

1.  Demography and health of Pugs under primary veterinary care in England.

Authors:  Dan G O'Neill; Elisabeth C Darwent; David B Church; Dave C Brodbelt
Journal:  Canine Genet Epidemiol       Date:  2016-06-10

2.  Impact of Facial Conformation on Canine Health: Brachycephalic Obstructive Airway Syndrome.

Authors:  Rowena M A Packer; Anke Hendricks; Michael S Tivers; Charlotte C Burn
Journal:  PLoS One       Date:  2015-10-28       Impact factor: 3.240

  2 in total

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