Further Polyenic and Polyynic Carboxamides and Sesamin from Achillea ptarmica.

The amides of various polyenic and polyynic carboxylic acids contained in the lipophilic extract from roots, leaves, and flowers of ACHILLEA PTARMICA were separated into several fractions by DCCC. Further separation was possible by subjecting these fractions to HPLC on silica gel (LiChrosorb) and CN-LiChrosorb. With this procedure, sesamin and 15 acid amides of unsaturated carboxylic acids were found. Structure elucidation of the compounds was carried out by means of UV-, IR-, (1)H-NMR spectroscopy and MS.