Literature DB >> 17268579

4-{N-[2-(1,3-Dioxo-1,3-dihydroisoindol-2-yl)-3-phenylpropionyl]anilino}-1-phenethylpiperidinium chloride methanol disolvate.

Ravil R Petrov, Ruben S Vardanyan, Gary S Nichol, Michael D Carducci, Shou-Wu Ma, Josephine Y Lai, Victor J Hruby.   

Abstract

The structure of the title compound, a fentanyl derivative with formula C(36)H(36)N(3)O(3) (+)·Cl(-)·2CH(3)OH, crystallizes as a racemic mixture. The organic cation has an extended conformation and the structure displays O-H⋯O, O-H⋯Cl and N-H⋯Cl hydrogen bonding.

Entities:  

Year:  2006        PMID： 17268579      PMCID： PMC1785114          DOI： 10.1107/S1600536806021817

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN： 1600-5368


  2 in total

1.  Potential affinity labels for the opiate receptor based on fentanyl and related compounds.

Authors:  B E Maryanoff; E J Simon; T Gioannini; H Gorissen
Journal:  J Med Chem       Date:  1982-08       Impact factor: 7.446

Review 2.  Adverse effects of opioid agonists and agonist-antagonists in anaesthesia.

Authors:  T A Bowdle
Journal:  Drug Saf       Date:  1998-09       Impact factor: 5.606
  2 in total
  1 in total

1.  Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity.

Authors:  Ravil R Petrov; Ruben S Vardanyan; Yeon S Lee; Shou-wu Ma; Peg Davis; Lucinda J Begay; Josephine Y Lai; Frank Porreca; Victor J Hruby
Journal:  Bioorg Med Chem Lett       Date:  2006-07-07       Impact factor: 2.823
  1 in total

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