Literature DB >> 17268503

Putting presenilins centre stage. Introduction to the Talking Point on the role of presenilin mutations in Alzheimer disease.

John Hardy1.   

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Year:  2007        PMID： 17268503      PMCID： PMC1796777          DOI： 10.1038/sj.embor.7400899

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


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  13 in total

Review 1.  Regulation of CRE-dependent transcription by presenilins: prospects for therapy of Alzheimer's disease.

Authors:  Vassilios Beglopoulos; Jie Shen
Journal:  Trends Pharmacol Sci       Date:  2005-12-07       Impact factor: 14.819

2.  Reconstitution of gamma-secretase activity.

Authors:  Dieter Edbauer; Edith Winkler; Joerg T Regula; Brigitte Pesold; Harald Steiner; Christian Haass
Journal:  Nat Cell Biol       Date:  2003-05       Impact factor: 28.824

3.  Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.

Authors:  M S Wolfe; W Xia; B L Ostaszewski; T S Diehl; W T Kimberly; D J Selkoe
Journal:  Nature       Date:  1999-04-08       Impact factor: 49.962

Review 4.  Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide.

Authors:  C Haass; D J Selkoe
Journal:  Cell       Date:  1993-12-17       Impact factor: 41.582

5.  Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.

Authors:  B De Strooper; P Saftig; K Craessaerts; H Vanderstichele; G Guhde; W Annaert; K Von Figura; F Van Leuven
Journal:  Nature       Date:  1998-01-22       Impact factor: 49.962

Review 6.  Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease.

Authors:  Bart De Strooper
Journal:  EMBO Rep       Date:  2007-02       Impact factor: 8.807

Review 7.  When loss is gain: reduced presenilin proteolytic function leads to increased Abeta42/Abeta40. Talking Point on the role of presenilin mutations in Alzheimer disease.

Authors:  Michael S Wolfe
Journal:  EMBO Rep       Date:  2007-02       Impact factor: 8.807

8.  Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway.

Authors:  Dragana Spasic; Alexandra Tolia; Katleen Dillen; Veerle Baert; Bart De Strooper; Stefan Vrijens; Wim Annaert
Journal:  J Biol Chem       Date:  2006-07-14       Impact factor: 5.157

Review 9.  The solved and unsolved mysteries of the genetics of early-onset Alzheimer's disease.

Authors:  Ekaterina Rogaeva
Journal:  Neuromolecular Med       Date:  2002       Impact factor: 3.843

10.  Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene.

Authors:  D Levitan; I Greenwald
Journal:  Nature       Date:  1995-09-28       Impact factor: 49.962
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  4 in total

1.  Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function.

Authors:  Sean M J McBride; Catherine H Choi; Brian P Schoenfeld; Aaron J Bell; David A Liebelt; David Ferreiro; Richard J Choi; Paul Hinchey; Maria Kollaros; Allison M Terlizzi; Neal J Ferrick; Eric Koenigsberg; Rebecca L Rudominer; Ai Sumida; Stephanie Chiorean; Kathleen K Siwicki; Hanh T Nguyen; Mark E Fortini; Thomas V McDonald; Thomas A Jongens
Journal:  J Neurosci       Date:  2010-07-14       Impact factor: 6.167

Review 2.  Reassessing the amyloid cascade hypothesis of Alzheimer's disease.

Authors:  Sanjay W Pimplikar
Journal:  Int J Biochem Cell Biol       Date:  2008-12-30       Impact factor: 5.085

3.  Molecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer's disease human skin fibroblasts.

Authors:  Graziella Mendonsa; Justyna Dobrowolska; Angela Lin; Pooja Vijairania; Y-J I Jong; Nancy L Baenziger
Journal:  PLoS One       Date:  2009-02-27       Impact factor: 3.240

4.  The Drosophila DmGluRA is required for social interaction and memory.

Authors:  Brian P Schoenfeld; Richard J Choi; Catherine H Choi; Allison M Terlizzi; Paul Hinchey; Maria Kollaros; Neal J Ferrick; Eric Koenigsberg; David Ferreiro; David A Leibelt; Steven J Siegel; Aaron J Bell; Thomas V McDonald; Thomas A Jongens; Sean M J McBride
Journal:  Front Pharmacol       Date:  2013-05-23       Impact factor: 5.810
  4 in total

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