| Literature DB >> 17268159 |
Selvaraj Saravanan1, Ramasundaram Srikumar, Sundaramahalingam Manikandan, Narayanaperumal Jeya Parthasarathy, Rathinasamy Sheela Devi.
Abstract
Hypercholesteremia is one of the risk factors for coronary artery disease. The present study highlights the efficacy of Ayurvedic herbal formulation Triphala (Terminalia chebula, Terminalia belerica, and Emblica officinalis) on total cholesterol, Low density lipoprotein (LDL), Very low density lipoprotein (VLDL), High density lipoprotein (HDL) and free fatty acid in experimentally induced hypercholesteremic rats. Four groups of rats were employed namely control, Triphala treated, hypercholesterolemia rats (4% Cholesterol + 1% cholic acid + egg yolk) and Triphala pre-treatment in hypercholesteremic rats. Results showed significant increase in the total cholesterol, LDL, VLDL, and free fatty acid in hypercholesteremic rats were significantly reduced in Triphala treated hypercholesteremic rats. The data demonstrated that Triphala formulation was associated with hypolipidemic effects on the experimentally induced hypercholesteremic rats.Entities:
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Year: 2007 PMID： 17268159 DOI： 10.1248/yakushi.127.385
Source DB: PubMed Journal: Yakugaku Zasshi ISSN： 0031-6903 Impact factor: 0.302