Literature DB >> 1726790

Reciprocal mesenchymal-epithelial interaction affecting prostate tumour growth and hormonal responsiveness.

L W Chung1, M E Gleave, J T Hsieh, S J Hong, H E Zhau.   

Abstract

A novel cell-cell recombination model was established to test the reciprocal mesenchymal (fibroblast)-epithelial interaction in the prostate gland. Both growth factors and ECM pathways were found to be actively engaged during cellular communications. The application of this cell-cell recombination concept to prostate cancer established a new human prostate cancer animal model in which the tumours actively secrete prostate specific antigen, a known human prostate cancer marker. This review explores the significance of mesenchymal-epithelial interaction in determining prostate hormonal responsiveness and prostate cell transformation and speculates on the potential roles of mesenchymal-epithelial interaction in prostate cancer growth and progression.

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Year:  1991        PMID： 1726790

Source DB:  PubMed          Journal:  Cancer Surv        ISSN： 0261-2429


  17 in total

Review 1.  Prostate cancer: a comprehensive review.

Authors:  S N Pentyala; J Lee; K Hsieh; W C Waltzer; A Trocchia; L Musacchia; M J Rebecchi; S A Khan
Journal:  Med Oncol       Date:  2000-05       Impact factor: 3.064

Review 2.  Cellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.

Authors:  Leanne M Cotton; Moira K O'Bryan; Barry T Hinton
Journal:  Endocr Rev       Date:  2008-01-23       Impact factor: 19.871

Review 3.  Fibroblasts are critical determinants in prostatic cancer growth and dissemination.

Authors:  L W Chung
Journal:  Cancer Metastasis Rev       Date:  1991-10       Impact factor: 9.264

Review 4.  Prostate epithelial differentiation is dictated by its surrounding stroma.

Authors:  L W Chung; R Davies
Journal:  Mol Biol Rep       Date:  1996       Impact factor: 2.316

5.  Establishment of a three-dimensional human prostate organoid coculture under microgravity-simulated conditions: evaluation of androgen-induced growth and PSA expression.

Authors:  H E Zhau; T J Goodwin; S M Chang; T L Baker; L W Chung
Journal:  In Vitro Cell Dev Biol Anim       Date:  1997-05       Impact factor: 2.416

6.  Establishment and characterization of a prostate cancer cell line from a prostatectomy specimen for the study of cellular interaction.

Authors:  Ruoxiang Wang; Gina C-Y Chu; Xudong Wang; Jason B Wu; Peizhen Hu; Asha S Multani; Sen Pathak; Haiyen E Zhau; Leland W K Chung
Journal:  Int J Cancer       Date:  2019-05-10       Impact factor: 7.396

7.  Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines.

Authors:  C M Witkowski; I Rabinovitz; R B Nagle; K S Affinito; A E Cress
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

Review 8.  Androgen receptor and growth factor signaling cross-talk in prostate cancer cells.

Authors:  Meng-Lei Zhu; Natasha Kyprianou
Journal:  Endocr Relat Cancer       Date:  2008-07-30       Impact factor: 5.678

9.  Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis.

Authors:  Shian-Ying Sung; Chia-Ling Hsieh; Andrew Law; Haiyen E Zhau; Sen Pathak; Asha S Multani; Sharon Lim; Ilsa M Coleman; Li-Chin Wu; William D Figg; William L Dahut; Peter Nelson; Jae K Lee; Mahul B Amin; Robert Lyles; Peter A J Johnstone; Fray F Marshall; Leland W K Chung
Journal:  Cancer Res       Date:  2008-12-01       Impact factor: 12.701

Review 10.  Prostate cancer progression. Implications of histopathology.

Authors:  J L Ware
Journal:  Am J Pathol       Date:  1994-11       Impact factor: 4.307
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