Literature DB >> 17267681

Importance of red patches diagnosed in cystoscopy for haematuria and lower urinary tract symptoms.

Herman Fernando1, Sreenivasa S Thota, Glyn Burtt, Nicholas Waterfall, Imtiaz Husain.   

Abstract

BACKGROUND: Biopsy of the red patches in the bladder, when found at cystoscopy, is routinely performed in urological practice. This is done to establish the sinister diagnosis of carcinoma-in-situ among other causes.
OBJECTIVE: To analyse the pathology of the red patches and to determine if routine biopsy of these patches is warranted. PATIENTS AND METHODS: This was a retrospective study conducted over a period of 36 months, in which 50 patients were identified, who underwent biopsies of their red patches. All patients with a history of bladder carcinoma and obvious bladder tumours were excluded from this study.
RESULTS: The mean age of the patients was 60.8 years. 25 patients had cystoscopy for lower urinary tract symptoms, 21 for haematuria and 4 for recurrent urinary tract infection. Carcinoma in situ was found in 4 (8%) patients, of whom only 2 had positive urine cytology.
CONCLUSION: It is prudent to perform a biopsy of all incidentally diagnosed red patches because of a major yield rate of carcinoma in situ. This procedure also picks up other important pathologies, which help in further management.

Entities:  

Mesh:

Year:  2007        PMID: 17267681      PMCID: PMC2599966          DOI: 10.1136/pgmj.2006.050112

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  7 in total

1.  Correlation of cystoscopic impression with histologic diagnosis of biopsy specimens of the bladder.

Authors:  S J Cina; J I Epstein; J M Endrizzi; W J Harmon; T M Seay; M P Schoenberg
Journal:  Hum Pathol       Date:  2001-06       Impact factor: 3.466

Review 2.  Time to abandon testing for microscopic haematuria in adults?

Authors:  Per-Uno Malmström
Journal:  BMJ       Date:  2003-04-12

3.  The plight of the patient with carcinoma in situ of the bladder.

Authors:  D C Utz; K A Hanash; G M Farrow
Journal:  J Urol       Date:  1970-02       Impact factor: 7.450

4.  Screening for bladder tumours in men aged 60-70 years with a bladder tumour marker (UBC) and dipstick-detected haematuria using both white-light and fluorescence cystoscopy.

Authors:  Hans Hedelin; Karin Jonsson; Karin Salomonsson; Hans Boman
Journal:  Scand J Urol Nephrol       Date:  2006

Review 5.  Fluorescence cystoscopy in the management of bladder cancer: a help for the urologist!

Authors:  Patrice Jichlinski; Hans-Jurg Leisinger
Journal:  Urol Int       Date:  2005       Impact factor: 2.089

6.  Biopsy of the red patch at cystoscopy: is it worthwhile?

Authors:  M J Swinn; M M Walker; L J Harbin; J M Adshead; R O'N Witherow; J A Vale; A Patel
Journal:  Eur Urol       Date:  2004-04       Impact factor: 20.096

Review 7.  Carcinoma in situ of the urinary tract.

Authors:  D C Utz; G M Farrow
Journal:  Urol Clin North Am       Date:  1984-11       Impact factor: 2.241

  7 in total

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