Literature DB >> 17266857

[Sydenham's chorea: report of a case treated with carbamazepine with excellent clinical response].

Ma M García González1, L Mayol Canals, P Villalobos Arévalo, M Vázquez Ruiz, A Cabacas García.   

Abstract

Sydenham's chorea is the most common cause of acquired chorea in childhood. This disorder is secondary to an autoimmune response against basal ganglia in the brain, induced by prior streptococcal infection. Chorea is a major criterion for the diagnosis of rheumatic fever and can also be the presenting feature of the disease. The incidence of rheumatic fever has been markedly decreased by improved socioeconomic conditions and increased antibiotic prescription. In the last two decades, however, this disease has reappeared and should be taken into account in the evaluation of children with movement disorders. Chorea is characterized by acute exacerbations that can cause substantial functional impairment and may warrant drug treatment. Carbamazepine has proven to be both efficacious and safe in the treatment of this condition. We present a case of rheumatic chorea, in which carbamazepine therapy produced excellent clinical response.

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Year:  2007        PMID: 17266857     DOI: 10.1157/13097365

Source DB:  PubMed          Journal:  An Pediatr (Barc)        ISSN: 1695-4033            Impact factor:   1.500


  2 in total

1.  Diffusion-weighted imaging in Sydenham's chorea.

Authors:  Hakan Gumus; Gulsum Gumus; Huseyin Per; Ali Yikilmaz; Mehmet Canpolat; Gamze Poyrazoglu; Nazmi Narin
Journal:  Childs Nerv Syst       Date:  2012-08-28       Impact factor: 1.475

2.  Chorea as the presenting feature of acute rheumatic fever in childhood; case reports from a low-prevalence European setting.

Authors:  Marta Illán Ramos; Belén Sagastizabal Cardelús; Adrián García Ron; Sara Guillén Martín; Arantxa Berzosa Sánchez; José Tomás Ramos Amador
Journal:  BMC Infect Dis       Date:  2021-04-07       Impact factor: 3.090

  2 in total

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