Literature DB >> 17266640

Recent advances in the development of agonists selective for beta1-type thyroid hormone receptor.

J Malm1, G J Grover, M Färnegårdh.   

Abstract

This mini-review will provide an overview on the recent design principles and structure-activity-relationship of beta-selective thyroid hormone receptor (TR) agonists. The prospects for the treatment of metabolic diseases as dyslipidemia with TRbeta-selective ligands are considerable enough so as to avoid cardiovascular acceleration mediated through TRalpha.

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Year:  2007        PMID： 17266640     DOI： 10.2174/138955707779317885

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  4 in total

1.  Site-specific basicities regulate molecular recognition in receptor binding: in silico docking of thyroid hormones.

Authors:  Gergő Tóth; Ferenc Baska; András Schretner; Akos Rácz; Béla Noszál
Journal:  Eur Biophys J       Date:  2013-08-02       Impact factor: 1.733

2.  Increasing Thyromimetic Potency through Halogen Substitution.

Authors:  Jordan Devereaux; Skylar J Ferrara; Tania Banerji; Andrew T Placzek; Thomas S Scanlan
Journal:  ChemMedChem       Date:  2016-10-12       Impact factor: 3.466

3.  Selective thyroid hormone receptor modulators.

Authors:  Girish Raparti; Suyog Jain; Karuna Ramteke; Mangala Murthy; Ravi Ghanghas; Sunita Ramanand; Jaiprakash Ramanand
Journal:  Indian J Endocrinol Metab       Date:  2013-03

4.  Bacterial biosensors for screening isoform-selective ligands for human thyroid receptors α-1 and β-1.

Authors:  Izabela Gierach; Jingjing Li; Wan-Yi Wu; Gary J Grover; David W Wood
Journal:  FEBS Open Bio       Date:  2012-08-15       Impact factor: 2.693
  4 in total

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