Literature DB >> 17266377

Metal triflate catalyzed reactions of alkenes, NBS, nitriles, and TMSN3: synthesis of 1,5-disubstituted tetrazoles.

Saumen Hajra1, Debarshi Sinha, Manishabrata Bhowmick.   

Abstract

A versatile and highly efficient protocol for the synthesis of 1,5-disubstituted tetrazoles has been developed by metal triflate catalyzed one-pot reaction of alkenes, NBS, nitriles, and TMSN3. Among the metal triflates, Zn(OTf)2 was found to be the best catalyst. Use of different combinations of alkenes and nitriles generate a variety of 1,5-disubstituted tetrazoles containing an additional alpha-bromo functionality of the N1-alkyl substituent.

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Year:  2007        PMID： 17266377     DOI： 10.1021/jo062432j

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  4 in total

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Journal:  J Mol Model       Date:  2016-04-15       Impact factor: 1.810

Review 2.  A review of syntheses of 1,5-disubstituted tetrazole derivatives.

Authors:  Afshin Sarvary; Ali Maleki
Journal:  Mol Divers       Date:  2014-10-02       Impact factor: 2.943

3.  Ru (III) catalyzed oxidation of aliphatic ketones by N-bromosuccinimide in aqueous acetic acid: a kinetic study.

Authors:  P Giridhar Reddy; K Ramesh; S Shylaja; K C Rajanna; S Kandlikar
Journal:  ScientificWorldJournal       Date:  2012-04-30

4.  Sustainable Generation of Ni(OH)2 Nanoparticles for the Green Synthesis of 5-Substituted 1H-Tetrazoles: A Competent Turn on Fluorescence Sensing of H2O2.

Authors:  Mita Halder; Md Mominul Islam; Pritam Singh; Anupam Singha Roy; Sk Manirul Islam; Kamalika Sen
Journal:  ACS Omega       Date:  2018-07-23
  4 in total

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