| Literature DB >> 17266046 |
J Herzog1, M Pinsker, M Wasner, F Steigerwald, S Wailke, G Deuschl, J Volkmann.
Abstract
Rarely, the postoperative management of patients with subthalamic deep brain stimulation (STN-DBS) is complicated by pharmacologically intractable dyskinesias. Here we report that in three of these patients additional stimulation of a proximal contact located within the subthalamic white matter may lead to a significant reduction of dyskinesias associated with STN-DBS. We propose that pallidofugal fiber tracts play a major role in the etiopathology of dyskinesias and their blockade through DBS may explain our observations.Entities:
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Year: 2007 PMID: 17266046 DOI: 10.1002/mds.21387
Source DB: PubMed Journal: Mov Disord ISSN: 0885-3185 Impact factor: 10.338