| Literature DB >> 17263583 |
Carmela Molinaro1, Jeffrey Mowat, Francis Gosselin, Paul D O'Shea, Jean-François Marcoux, Rémy Angelaud, Ian W Davies.
Abstract
We report herein a simple, scalable, transition-metal-free approach to the synthesis of alpha-aryl methyl ketones from diazonium tetrafluoroborate salts under mild conditions. This methodology uses easily accessible and nontoxic starting material and was applied to the multi-kilogram-scale preparation of 1-(3-bromo-4-methylphenyl)propan-2-one.Entities:
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Year: 2007 PMID： 17263583 DOI： 10.1021/jo062483g
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354