Literature DB >> 17262180

[Respiratory failure in thoracic spine injuries. Does the timing of dorsal stabilization have any effect on the clinical course in multiply injured patients?].

Thomas M Frangen1, S Ruppert, G Muhr, C Schinkel.   

Abstract

BACKGROUND: Proper timing of stabilization for spinal injuries is discussed controversially. Whereas early repair of long bone fractures is known to reduce complications, few studies exist that investigate this issue in acute spinal trauma. In particular, the importance of coexisting lung injuries has to be determined, as it might influence clinical course and outcome.
MATERIAL AND METHODS: We investigated retrospectively 30 severely injured patients who were stabilized dorsally for fractures of the thoracic and upper lumbar spine. The mean Injury Severity Score (ISS) was 41 points. Patients were divided into two groups: group I: acute trauma/stabilization <72 h and group II: acute trauma/stabilization >72 h. All patients in groups I and II presented radiological or clinical signs of lung contusion.
RESULTS: The average duration of the procedures in group I was 199 min (115-312 min) and in group II 139 min (98-269 min). Intraoperative blood loss and P(a)O(2)/F(i)O(2)-ratio did not differ significantly between the two groups. The overall in ICU and hospital stay was significantly shorter in group I: 16 days (1-78 days) versus 24 days (7-86 days) in the late group II. Postoperative respirator therapy was necessary in group I for 15 days (0-79 days) and in group II for 19 days (4-31 days). The mortality rate was 10% in this series.
CONCLUSION: Our data provide further evidence that early stabilization of spinal injuries is safe in severely injured patients, does not impair perioperative lung function, and results in a reduced overall ICU and hospital stay. Further prospective randomized investigations are warranted to prove these results.

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Year:  2007        PMID: 17262180     DOI: 10.1007/s00132-007-1049-8

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  23 in total

1.  Epidemiology of incident spinal fracture in a complete population.

Authors:  R Hu; C A Mustard; C Burns
Journal:  Spine (Phila Pa 1976)       Date:  1996-02-15       Impact factor: 3.468

2.  Treatment of thoracolumbar trauma: comparison of complications of operative versus nonoperative treatment.

Authors:  G R Rechtine; D Cahill; A M Chrin
Journal:  J Spinal Disord       Date:  1999-10

3.  Early versus delayed stabilization of femoral fractures. A prospective randomized study.

Authors:  L B Bone; K D Johnson; J Weigelt; R Scheinberg
Journal:  J Bone Joint Surg Am       Date:  1989-03       Impact factor: 5.284

4.  Biochemical changes after trauma and skeletal surgery of the lower extremity: quantification of the operative burden.

Authors:  H C Pape; R E Schmidt; J Rice; M van Griensven; R das Gupta; C Krettek; H Tscherne
Journal:  Crit Care Med       Date:  2000-10       Impact factor: 7.598

5.  Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers.

Authors:  H C Pape; M van Griensven; J Rice; A Gänsslen; F Hildebrand; S Zech; M Winny; R Lichtinghagen; C Krettek
Journal:  J Trauma       Date:  2001-06

6.  Thoracic spinal injuries: operative treatments and neurologic outcomes.

Authors:  George S Sapkas; Panayiotis J Papagelopoulos; Stamatios A Papadakis; George S Themistocleous; Dimitrios P Stathakopoulos; Panos Efstathiou; Despoina Sapoutzi-Krepia; Athanasios Ch Badekas
Journal:  Am J Orthop (Belle Mead NJ)       Date:  2003-02

7.  Risk factors for respiratory failure following operative stabilization of thoracic and lumbar spine fractures.

Authors:  Timothy P McHenry; Sohail K Mirza; JingJing Wang; Charles E Wade; Grant E O'Keefe; Andrew T Dailey; Martin A Schreiber; Jens R Chapman
Journal:  J Bone Joint Surg Am       Date:  2006-05       Impact factor: 5.284

8.  Assessment of the relationship between timing of fixation of the fracture and secondary brain injury in patients with multiple trauma.

Authors:  D C Kalb; A L Ney; J L Rodriguez; D M Jacobs; J M Van Camp; R T Zera; G L Rockswold; M A West
Journal:  Surgery       Date:  1998-10       Impact factor: 3.982

9.  Early surgery for thoracolumbar spine injuries decreases complications.

Authors:  Jeffrey G Chipman; William E Deuser; Greg J Beilman
Journal:  J Trauma       Date:  2004-01

10.  Posttraumatic inflammatory response, secondary operations, and late multiple organ failure.

Authors:  C Waydhas; D Nast-Kolb; A Trupka; R Zettl; M Kick; J Wiesholler; L Schweiberer; M Jochum
Journal:  J Trauma       Date:  1996-04
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  3 in total

1.  Complications are reduced with a protocol to standardize timing of fixation based on response to resuscitation.

Authors:  Heather A Vallier; Timothy A Moore; John J Como; Patricia A Wilczewski; Michael P Steinmetz; Karl G Wagner; Charles E Smith; Xiao-Feng Wang; Andrea J Dolenc
Journal:  J Orthop Surg Res       Date:  2015-10-01       Impact factor: 2.359

2.  Possible advantages of early stabilization of spinal fractures in multiply injured patients with leading thoracic trauma - analysis based on the TraumaRegister DGU®.

Authors:  Sven Hager; Helge Eberbach; Rolf Lefering; Thorsten O Hammer; David Kubosch; Christoph Jäger; Norbert P Südkamp; Jörg Bayer
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2020-05-24       Impact factor: 2.953

3.  Thoracic hyperextension injury with complete "bony disruption" of the thoracic cage: Case report of a potentially life-threatening injury.

Authors:  James Bailey; Todd Vanderheiden; Clay Cothren Burlew; Sarah Pinski-Sibbel; Janeen Jordan; Ernest E Moore; Philip F Stahel
Journal:  World J Emerg Surg       Date:  2012-05-15       Impact factor: 5.469

  3 in total

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