| Literature DB >> 1726164 |
C Ferri1, F Greco, G Longombardo, P Palla, A Moretti, E Marzo, P V Fosella, G Pasero, S Bombardieri.
Abstract
The prevalence of antibodies against hepatitis C virus (anti-HCV) in an unselected series of 45 mixed cryoglobulinemia patients was assessed by an enzyme linked immunosorbent assay (Chiron ELISA HCV, Second Generation). The anti-HCV specificity was evaluated by a recombinant based immunoblot assay (Chiron RIBA HCV, Second Generation Assay). HBV-related markers and HIVAb were detected in the same samples. The prevalence of anti-HCV observed in mixed cryoglobulinemia was compared with 80 patients with other immunological systemic diseases. Anti-HCV were found in 91% of mixed cryoglobulinemia patients, and confirmed by RIBA in all cases; on the other hand, anti-HCV were practically absent in other control diseases. HBV markers were recorded in 49% of mixed cryoglobulinemia subjects; while HIVAb were constantly absent. These data give us new insights into the etiopathogenesis of mixed cryoglobulinemia.Entities:
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Year: 1991 PMID： 1726164 DOI： 10.1007/bf01726453
Source DB: PubMed Journal: Infection ISSN： 0300-8126 Impact factor: 3.553