Emanuela Caroli1, Maurizio Salvati, Luigi Ferrante. 1. Department of Neurological Sciences, Neurosurgery, St. Andrea Hospital, University of Rome "La Sapienza", Rome, Italy. manucarol2000@yahoo.it
Abstract
AIMS AND BACKGROUND: Classical multiple sclerosis plaques usually have typical features on gadolinium-enhanced MRI scan. This non-neoplastic demyelinating process of the central nervous system generally does not produce focal space-occupying lesions associated with ring enhancement. However, atypical appearance of demyelinating lesions simulating a brain tumor is a possible well-known phenomenon. METHODS: We present our experience with 4 cases of multiple sclerosis indistinguishable clinically and neuroradiologically from a cerebral tumor. All patients underwent surgery. RESULTS: Histological examinations of all cases were positive for multiple sclerosis plaques. CONCLUSIONS: The presented cases demonstrate the importance of considering a demyelinating disease in the differential diagnosis of a tumor-like brain lesion.
AIMS AND BACKGROUND: Classical multiple sclerosis plaques usually have typical features on gadolinium-enhanced MRI scan. This non-neoplastic demyelinating process of the central nervous system generally does not produce focal space-occupying lesions associated with ring enhancement. However, atypical appearance of demyelinating lesions simulating a brain tumor is a possible well-known phenomenon. METHODS: We present our experience with 4 cases of multiple sclerosis indistinguishable clinically and neuroradiologically from a cerebral tumor. All patients underwent surgery. RESULTS: Histological examinations of all cases were positive for multiple sclerosis plaques. CONCLUSIONS: The presented cases demonstrate the importance of considering a demyelinating disease in the differential diagnosis of a tumor-like brain lesion.
Authors: Frederico Carvalho de Medeiros; Lucas Alverne Freitas de Albuquerque; Jose Eymard Homem Pittella; Renata Brant de Souza; Antonio Pereira Gomes Neto; Paulo Pereira Christo Journal: Case Rep Neurol Med Date: 2014-04-15