Literature DB >> 17260244

A New Rosmarinic Acid Derivative from Isodon oresbius.

H Huang1, Q R Chao, R X Tan, H D Sun, D C Wang, J Ma, S X Zhao.   

Abstract

Phytochemical reinvestigation of ISODON ORESBIUS afforded, in addition to oleanolic acid, ursolic acid, sodoponin, astragalin, and quercetin-3- O-glucoside, three known (oresbiusin A, rosmarinic acid and methyl rosmarinate) and a new rosmarinic acid derivative as well as an ENT-kaurene diterpenoid, neo-angustifolin, characterized as a separated component for the first time. By a combination of 1D- and 2D-NMR techniques the structure of the new compound was established as butyl rosmarinate. The IN VITRO antifungal assay showed that neoangustifolin was active against CANDIDA ALBICANS with the MIC being 50 microg/ml.

Entities:  

Year:  1999        PMID： 17260244     DOI： 10.1055/s-2006-960451

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  3 in total

Review 1.  A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight.

Authors:  Huaquan Guan; Wenbin Luo; Beihua Bao; Yudan Cao; Fangfang Cheng; Sheng Yu; Qiaoling Fan; Li Zhang; Qinan Wu; Mingqiu Shan
Journal:  Molecules       Date:  2022-05-20       Impact factor: 4.927

2.  Short Chain (≤C4) Esterification Increases Bioavailability of Rosmarinic Acid and Its Potency to Inhibit Vascular Smooth Muscle Cell Proliferation.

Authors:  Tina Blažević; Gottfried Reznicek; Limin Ding; Gangqiang Yang; Patricia Haiss; Elke H Heiss; Verena M Dirsch; Rongxia Liu
Journal:  Front Pharmacol       Date:  2021-01-21       Impact factor: 5.810

3.  Possible neuroprotective effects of amide alkaloids from Bassia indica and Agathophora alopecuroides: in vitro and in silico investigations.

Authors:  Ahmed Othman; Ahmed M Sayed; Yhiya Amen; Kuniyoshi Shimizu
Journal:  RSC Adv       Date:  2022-07-01       Impact factor: 4.036
  3 in total

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