BACKGROUND: Desmoid tumors have a tendency to recur locally, and traditionally they have been treated surgically. No treatment is sometimes indicated, however; this requires a morphological diagnosis that is not based on a surgical specimen. In this study we aimed to identify the diagnostic accuracy of needle and core biopsy for the morphological diagnosis of desmoid. METHODS: We compared the diagnostic accuracy of fine-needle aspiration (FNA) and core needle biopsy (CNB) in 69 and 26 patients, respectively, who had had surgical resections for desmoid. We also reviewed 15 additional cases that had been incorrectly diagnosed as desmoid on FNA but which had different diagnoses after surgery. RESULTS: FNA-based diagnoses of desmoid/fibromatosis were rendered in 35 of 69 cases, and other benign spindle cell proliferations in 26 cases and spindle cell sarcoma in the remaining 4 cases. All 26 CNBs were either suggested to correspond to desmoid (24) or other benign spindle cell lesions (2). Of the 15 FNAs incorrectly diagnosed as desmoid, 2 were found to be sarcomas. INTERPRETATION: FNA is fairly reliable for recognition of the benign nature of desmoids. Occasional over- and under-diagnosis of malignancy can occur, however. CNB appears to be more reliable.
BACKGROUND:Desmoid tumors have a tendency to recur locally, and traditionally they have been treated surgically. No treatment is sometimes indicated, however; this requires a morphological diagnosis that is not based on a surgical specimen. In this study we aimed to identify the diagnostic accuracy of needle and core biopsy for the morphological diagnosis of desmoid. METHODS: We compared the diagnostic accuracy of fine-needle aspiration (FNA) and core needle biopsy (CNB) in 69 and 26 patients, respectively, who had had surgical resections for desmoid. We also reviewed 15 additional cases that had been incorrectly diagnosed as desmoid on FNA but which had different diagnoses after surgery. RESULTS: FNA-based diagnoses of desmoid/fibromatosis were rendered in 35 of 69 cases, and other benign spindle cell proliferations in 26 cases and spindle cell sarcoma in the remaining 4 cases. All 26 CNBs were either suggested to correspond to desmoid (24) or other benign spindle cell lesions (2). Of the 15 FNAs incorrectly diagnosed as desmoid, 2 were found to be sarcomas. INTERPRETATION: FNA is fairly reliable for recognition of the benign nature of desmoids. Occasional over- and under-diagnosis of malignancy can occur, however. CNB appears to be more reliable.
Authors: Armanda De Marchi; Elena Maria Brach del Prever; Alessandra Linari; Simona Pozza; Lucia Verga; Ugo Albertini; Marco Forni; Gian Carlo Gino; Alessandro Comandone; Adalberto Maria Brach del Prever; Raimondo Piana; Carlo Faletti Journal: Eur Radiol Date: 2010-06-27 Impact factor: 5.315
Authors: Yaseen Oweis; David R Lucas; Catherine J Brandon; Gandikota Girish; Jon A Jacobson; David P Fessell Journal: Skeletal Radiol Date: 2011-12-31 Impact factor: 2.199
Authors: Sina Kasraeian; Daniel C Allison; Elke R Ahlmann; Alexander N Fedenko; Lawrence R Menendez Journal: Clin Orthop Relat Res Date: 2010-11 Impact factor: 4.176
Authors: Pablo Moura de Andrade Lima; Marcelo Parente Oliveira; Hilton Justino da Silva; Roberto José Vieira de Mello Journal: Acta Ortop Bras Date: 2012 Impact factor: 0.513